Burrow spent his entire rugby league career with Leeds Rhinos and helped them win eight Super League titles.
He retired in 2017 but two years later it was revealed Burrow had been diagnosed with MND and, after he raised millions to help build a new care centre for MND patients alongside former team-mate Kevin Sinfield, his death was confirmed by his former club on Sunday evening.
Prince William, in a statement on his official X account, said: "A legend of rugby league, Rob Burrow had a huge heart. He taught us 'in a world full of adversity, we must dare to dream'. Catherine and I send our love to Lindsey, Jackson, Maya and Macy."
Rob Burrow holds a Leeds flag aloft in 2017. He won eight Super League titles with the Rhinos. (AP PHOTO)
A statement from Leeds read: "It is with deep sadness that we announce the death of our beloved son, husband, father, brother and friend. Rob has always been a true inspiration throughout his life whether that was on the rugby league field or during his battle with MND.
"He never allowed others to define what he could achieve and believed in his own ability to do more. The outpouring of love and support that Rob and the whole Burrow family have received over the last four and a half years meant so much to Rob.
Rugby Football League chairman Simon Johnson said: "This devastating news has united all in rugby league in sadness and the many others who have been touched and inspired by the courageous response of Rob, his family and friends since his diagnosis in December 2019."
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