Round one kicks off on April 18, with the highlight a fierce rivalry contest between Avenel and reigning premier Nagambie.
Plenty of eyes will turn to Ardmona Recreation Reserve as well to see Shane Crawford's debut as coach of the Bush Cats.
Ardmona hosts Violet Town in the round one clash, while other fixtures pit Lancaster against Girgarre and Tallygaroopna against Merrigum.
Shepparton East will host Dookie United as Longwood travels to Murchison-Toolamba, while Undera will battle Rushworth and Stanhope will wait an extra week to hit the ground running due to a bye.
A football grand final rematch will take place in round six when the Lakers host Tallygaroopna, while Stanhope and Dookie do not meet again on the netball court until round 10.
Only three matches will take place in round eight — which is the Queen's Birthday weekend — while round 16 will be split across two weekends in August.
Most of the competition will take to the field and court on Anzac Day, but clashes between Rushworth and Murchison-Toolamba, Merrigum and Lancaster and Stanhope and Undera will be held on Sunday, April 26.
Merrigum and Girgarre (round four), Undera and Lancaster (round 10) and Murchison-Toolamba and the Bulldogs (round 14) will also feature in Sunday contests throughout the season.
The grand final will be held on September 19.
Other exciting ventures this season will include the addition of an 11-and-under netball competition and an under-12 football grade to help clubs include more junior players and their families in the game day experience of the league.