Tedesco's axing from the Blues for next week's State of Origin opener against Queensland will leave the Australian captain available for full club duty during the interstate representative period for the first time since he joined the Roosters in 2018.
AAP can reveal the Roosters have only won 12 of 26 games during Tedesco's run of 22 consecutive Origin appearance for NSW at a strike rate of just 46 per cent.
But while the Bondi-based glamour club have won eight from 11 matches without Tedesco on deck while he's on Origin duties, it's the side's galling four-from-15 success rate when the superstar No.1 backs up during the gruelling series that may surprise - and alarm - Roosters fans.
James Tedesco (right) has been a mainstay for the Blues in State of Origin series. (Mark Evans/AAP PHOTOS)
Either way, teammates are relishing having a fresh Tedesco against North Queensland on Sunday and presumably the entire Origin series unless the 31-year-old earns a recall.
"It's massive for us," centre Joey Many said on Tuesday.
"Usually he's always away, but I'm happy that he's going to be playing with us this week.
"He's a champion player. He's done pretty much everything in the game.
"Obviously you want to see him play in Origin, but he's been playing awesome all year.
"I just try to run off him. He's been giving me some great ball lately."
Halfback Sam Walker expects Tedesco to bounce back from his Origin snubbing "like he always does".
"He's going to kill it," Walker said, predicting the Roosters having the influential fullback on hand for more games will only enhance their prospects of emerging from Origin as Penrith's biggest threat to a fourth straight premiership.
"It's always an interesting time of the year. It's  make or break for a lot of clubs that sort of border in there and they might lose a couple of players.
"I think we're in a really good position as a club with the depth we have.
"Obviously Penrith are a class team - they've won the last three conferences.
"It's no secret that they'll be in amongst it at the end of the year.
"We had an opportunity at the start of the year to beat them and we weren't up to that.
"But I feel like we've really progressed as a club and as a team over the last five or six weeks to put ourselves in a position.
"I believe we were the best team and that we'll be there at the end of the year, and that's the confidence that we're instilling at the club at the moment."
HOW THE SYDNEY ROOSTERS HAVE FARED WITH AND WITHOUT JAMES TEDESCO DURING STATE OF ORIGIN SINCE 2018:
WITHOUT TEDESCO 2018-2023 - won 8, lost 3
beat Wests Tigers 16-14beat Gold Coast 20-12beat Canterbury 38-12beat Wests Tigers 24-16lost to North Queensland 15-12beat Gold Coast 35-34beat Canterbury 22-16beat North Queensland 34-18lost to Canberra 22-16beat Newcastle 18-16lost to Melbourne 30-16WITH TEDESCO - won 4, lost 11
beat Newcastle 18-16beat Penrith 32-6lost to Melbourne 9-8lost to Penrith 19-10lost to Melbourne 14-12lost to Penrith 38-12lost to Melbourne 46-0lost to Melbourne 26-18lost to Parramatta 26-16lost to Penrith 26-18beat St George Illawarra 54-26beat Canterbury 25-24lost to Penrith 30-6lost to Canberra 20-18lost to Manly 18-16
ROOSTERS DURING ORIGIN SERIES 2018-23 - won 12, lost 14
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