The remarks by Nasser Kanaani, the spokesman for Iran's Foreign Ministry, came three days after Rushdie was wounded in New York state. The writer has been taken off a ventilator and is "on the road to recovery," according to his agent.
Rushdie, 75, has faced death threats for more than 30 years over his novel "The Satanic Verses," whose depiction of the Prophet Muhammad was seen by some Muslims as blasphemous.
In 1989, Iran's supreme leader, Ayatollah Ruhollah Khomeini, issued a fatwa, or Islamic edict, demanding the author's death, and while Iran has not focused on Rushdie in recent years, the decree still stands.
Also, a semiofficial Iranian foundation had posted a bounty of over $US3 million ($A4.3 million) for the killing of the author. It has not commented on the attack.
"Regarding the attack against Salman Rushdie in America, we don't consider anyone deserving reproach, blame or even condemnation, except for (Rushdie) himself and his supporters," Kanaani said.
"In this regard, no one can blame the Islamic Republic of Iran," he added. "We believe that the insults made and the support he received was an insult against followers of all religions."
Iran has denied carrying out other operations abroad against dissidents in the years since the country's 1979 Islamic Revolution, though prosecutors and Western governments have attributed such attacks to Tehran.
Rushdie was attacked on Friday as he was about to give a lecture. He suffered a damaged liver and severed nerves in an arm and an eye, according to his agent, Andrew Wylie. Rushdie is likely to lose the eye, Wylie said.
His alleged assailant, Hadi Matar, pleaded not guilty to attempted murder and assault.
Matar, 24, was born in the US to parents who emigrated from Yaroun in southern Lebanon near the Israeli border, according to the village's mayor.
Matar lived in New Jersey with his mother, who told London's Daily Mail her son became moody and more religious after a month-long trip to Lebanon in 2018.
"I was expecting him to come back motivated, to complete school, to get his degree and a job. But instead he locked himself in the basement. He had changed a lot, he didn't say anything to me or his sisters for months," Silvana Fardos said.
Village records in Yaroun show Matar holds Lebanese citizenship and is a Shiite, an official there said. The official, who spoke on condition of anonymity, said Matar's father lives there but has been in seclusion since the attack.
Police in New York have offered no motive for the attack, though District Attorney Jason Schmidt alluded to the bounty on Rushdie in arguing against bail during a hearing over the weekend.
"Even if this court were to set a million dollars bail, we stand a risk that bail could be met," Schmidt said.
In his remarks on Monday, Kanaani implied Rushdie brought the attack on himself.
"Salman Rushdie exposed himself to popular anger and fury through insulting the sacredness of Islam and crossing the red lines of over 1.5 billion Muslims and also red lines of followers of all divine religions," Kanaani said.
While fatwas can be revoked, Iran's current supreme leader, Ayatollah Ali Khamenei, who took over after Khomeini's death, has never done so. As recently as 2017, Khamenei said: "The decree is as Imam Khomeini issued."
