Hawthorn's push for a finals berth has hit a stumbling block with ruckman Ben McEvoy sidelined following surgery to repair a fractured cheekbone.
The 28-year-old suffered the injury to his left cheekbone in a last-quarter head clash with the Western Bulldogs' Josh Dunkley.
The eighth-placed Hawks confirmed McEvoy underwent surgery on Sunday and are unsure how many games he will miss.
He will definitely miss this week's clash with Brisbane in Launceston and most likely the round 18 clash with Carlton.
St Kilda also lost a key big man at the weekend, Paddy McCartin to miss at least a fortnight with a foot sprain.
The injury to his left foot occurred during the first quarter in Saturday's loss to Port Adelaide at Adelaide Oval.
"Paddy played out the game with some discomfort and while not overly serious, it will require him to spend time in a moon boot this week," Saints football chief Simon Lethlean said.
"It's obviously a frustrating setback, but thankfully a fairly minor one that should only keep him out for two-three weeks."
Collingwood's injury woes continued, with Will Hoskin-Elliott and Flynn Appleby joining their casualty list.
But Darcy Moore, Travis Varcoe and Josh Smith all made successful returns in the VFL on the weekend as they come back from hamstring injuries.
Moore is particularly important, given Lynden Dunn's season-ending knee injury, and the Magpies badly need him back to play as a key defender.
It is unclear whether Moore will return for next Sunday's MCG match against West Coast.
The Eagles could regain star forwards Josh Kennedy and Jack Darling from injury for the big clash, with the two teams in the top four.
Hoskin-Elliott has a badly bruised shin and Appleby is nursing a hamstring injury after Sunday's bruising win over Essendon at the MCG.
The Bombers also lost Patrick Ambrose to a hamstring injury, while Jake Stringer and Travis Myer played out the game with calf muscle problems.
Richmond defender Nathan Broad also hurt his cheekbone on Friday night in the win over Adelaide, while Jack Graham has a dislocated shoulder.