The Hard Quiz host famously won three years ago after launching a campaign ridiculing the award as well as his competition.
Gleeson has tried this strategy again in 2022, posting on Twitter that he would be embarrassed to win more than once.
"I'm not campaigning this year for the Gold Logie. Do not vote for me," he said.
The ABC presenter is up against some big names from commercial television; Hamish Blake, Julia Morris, Karl Stefanovic, Melissa Leong, Ray Meagher and Sonia Kruger.
The awards are being held on the the Gold Coast on Sunday night after a two-year hiatus due to COVID-19.
While Gold Logie campaign antics are a feature again, there have been some changes since the last time the awards were staged.
The Silver Logie for most popular presenter will be renamed the Bert Newton Award in honour of the late presenter, who died in October.
Old Moonface, as he was affectionately known, hosted the Logies 19 times and won the coveted Gold Logie in 1979, 1981, 1982 and 1984.
A new Silver Logie will also be awarded for the most popular actor in an international program.
The night will also feature a tribute to the long-running soapie Neighbours, a week after the show filmed its final scenes.
First broadcast in 1985, it was cancelled in March after nearly 9000 episodes.
The Logies will be broadcast on Channel Nine with red carpet coverage from 7pm AEST and awards presented from 7.30pm.
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