Man arrested, suspect on the run after fatal stabbing

A file photo of police tape
Victoria police found a man with fatal stab wounds at a home in Thomastown, Melbourne. -AAP Image

A man has been arrested and a second suspect is on the run over a fatal stabbing at a home in Melbourne's inner north.

Police were called to a Thomastown home about 8.40pm on Thursday and found an unconscious 36-year-old Doreen man with stab wounds.

He died at the property, on Victoria Drive, despite efforts to resuscitate him.

A 45-year-old Glenroy man was arrested at the scene, while detectives are searching for a second person.

"At this early stage in the investigation, the incident appears to be a targeted attack," a police spokeswoman said.

Police want to speak to anyone with information about the stabbing, or those in the area who may have CCTV or dash-cam footage.