Shakira shared a statement on social media on Sunday, saying she was in hospital and doctors had informed her she was not in condition to perform.
"I am very sad that I will not be able to take the stage today. I have been deeply emotional and excited about reuniting with my beloved Peruvian audience," she said.
The singer arrived in Peru on Friday evening, where she was scheduled to perform on Sunday and Monday.
The country is the second stop on her Latin American tour, Las Mujeres Ya No Lloran, following two nights in Brazil last week.
Latin fans have given Shakira a warm welcome, with crowds gathering at airports to greet her.
"Thank you for such an emotional welcome, Lima!" she posted Saturday on Instagram.
In her statement, Shakira said she hoped to recover soon.
"My plan is to perform this show as soon as possible. My team and the promoter are already working on a new date," she said.
The singer is touring in support of her latest album, Las Mujeres Ya No Lloran, in which she channels her highly publicised divorce into music.
The record includes the global hit Shakira: Bzrp Music Sessions, Vol. 53 and won best Latin pop album at the 2024 Grammy Awards earlier in February.
Shakira's tour continues across Latin America before heading to Canada and the US in May for a series of concerts through June.
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