Police were called to the Friends star's home in Bel Air on Monday after an elderly man "gained access" to her home after driving into the gate.
The suspect, "approximately 70 years of age, rammed his vehicle through the gate to the residence and gained access to the property", a Los Angeles Police Department spokesperson told People.
"There was a security guard on premises who was able to detain that suspect until officers arrived, at which time they took him into custody without incident.
"The resident was home at the time."
The suspect suffered minor injuries, but no one else was hurt in the incident.
The man was arrested with changes pending, although People reported he was likely to be charged with felony vandalism.
Police sources told ABC News: "The incident does not appear to have been an accident, though there is also nothing to indicate yet that the driver was targeting Aniston.
"The suspect, who has a minor criminal history, was not actively being investigated for anything involving Aniston before the incident."