Darcy was sidelined for Fremantle's first four games of the season after undergoing surgery on his knee and ankle during the summer.
The 26-year-old had also been plagued by injuries over the previous two seasons, and he flew to Qatar in January to find long-term answers to his troubles.
Darcy was monstered by Melbourne ruckman Max Gawn a fortnight ago, but he took a huge stride forward last week with 36 hitouts and five clearances in Fremantle's 18-point win over Adelaide.
Jackson, who has missed the past three weeks with a hamstring injury, is set to join Darcy in the side for Friday night's clash with St Kilda at Marvel Stadium.
Darcy is still in the process of building his form and fitness, and he opened up about the challenge of playing top-level football after missing most of the summer.
"It's tough. I just feel like a baby giraffe out there sometimes," Darcy said.
"Understanding to be strong in the contest, watch the ball, your touch - all that sort of thing takes a while to come back.
"I didn't get any pre-season at all. So I'm going to build every week.
"It's tough, but it's fun. It's football.
"I'm running around playing footy and playing in front of 53,000 rather than being in rehab, so I'll take this any day of the week."
When Jackson joined Fremantle at the end of 2022, much was touted about what he could achieve partnering Darcy.
Injuries have restricted the amount of time the duo have spent together, especially over the past 18 months, but they will partner up for the first time in 2025 in Friday's clash with St Kilda.
"I'm pretty excited," Darcy said.
"Me and 'Dogga', we haven't played too much footy over the last little bit, and the quality of football he was playing at the start of the year was very impressive.
"So I'd love to have the big fella back. I love him and love playing with him, so it'll be good fun.
"Once we get a run together, we feel like we could be really special together."
Fremantle (4-3) need a win over St Kilda (3-4) to prove they are a genuine finals contender.
St Kilda are desperate to rebound following losses to GWS (28 points), Western Bulldogs (71 points) and Brisbane (45 points).
