In a fine final but one that never quite hit the extraordinary heights of their Roland-Garros thriller five weeks earlier, Sinner proved too icily consistent for the erratic champion on a warm afternoon on Centre Court on Sunday, prevailing 4-6 6-4 6-4 6-4 to earn his fourth grand slam title.
The 23-year-old world No.1 recovered from losing the first set, which Alcaraz wrapped up with the shot of the match, to then dominate proceedings and seal victory in four minutes over three hours.
"This was only a dream, it was far away where I'm from," Sinner told the crowd after collecting the trophy from Kate, Princess of Wales. "I'm just living my dream, it's amazing."
Alcaraz had pulled off an incredible escape in Paris when he saved three championship points in a five-set, five-hour 29-minute epic, but this time Sinner was not about to let him off the hook as he constantly applied the pressure with his suffocatingly accurate and powerful groundstrokes.
It was his first victory over Alcaraz in his last six attempts as he handed the 22-year-old Spaniard his first defeat in a grand slam final.
Alcaraz had been on a career-best 24-match unbeaten run, and had won 20 matches in a row at the All England Club, including victories against Novak Djokovic in the 2023 and 2024 finals, yet he couldn't join the elite group to have won three in a row.