Colombia's Luis Diaz scored twice in four minutes to lead Colombia to victory over Brazil. -AP
Brazil have lost their second consecutive World Cup qualifier as Colombia fought back to win 2-1 against the five-times champions, who are winless in the last three games and dropped to fifth in the South American standings.
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It was a cathartic evening for Liverpool forward Luis Diaz who, just a few days after Colombia guerrillas freed his kidnapped father, scored twice within four minutes late in the second-half to give his country the shock win, after Brazil got an early lead with a Gabriel Martinelli strike.
In Buenos Aires, gritty Uruguay got a statement win beating Lionel Messi's Argentina 2-0 at their iconic Bombonera stadium thanks to goals from Ronald Araujo and Darwin Nunez in each half.
Uruguay were the better side from start to finish and climbed to second in the standings on 10 points with the win, two behind leaders Argentina who dropped their first points in five games in the South America World Cup qualifiers.
Colombia are third on nine points, one ahead of Venezuela who were held to a goalless draw at home by sixth-placed Ecuador, who are one behind Brazil on seven points.