With all 12 Super Rugby Pacific sides playing at Melbourne's AAMI Park over three days, the Reds, Waratahs and Brumbies all left as winners while the Rebels had a narrow loss to the Hurricanes.
After a disappointing 21-point loss to the Chiefs in round one, the Reds started their Sunday afternoon clash with a bang and never looked back.
They scored 10 tries to three to bank a crushing 71-20 win - their biggest ever score in Super Rugby.
Coach Brad Thorn was pleased with the Reds' response after their opening loss.
"A week ago we were hurting around the score ... we needed a response and the guys did that in spades today," Thorn said.
Force coach Simon Cron said his players lost confidence after they failed to stick to defensive system, likening the match to a "car crash".
"In terms of performance it was a poor one by us and they played really well," Cron said.
"The key thing for us is sometimes if you're off by 10 per cent Super Rugby can look like a car crash and that's what I saw today.
"We fix that and give the boys clarity around where we can be better, that's what we've got to do now."
Queensland looked to have scored after 30 seconds thanks to a 30-metre break by Jordan Petaia, with the silky fullback gliding through the defence and off-loading to Josh Flook, however the centre put his foot on the sideline.
Queensland fans didn't have to wait long to celebrate, with two tries scored by the six-minute mark, with lock Ryan Smith first across the tryline.
A minute later Petaia showed off his array of skills, following up his own thumping kicking down-field and collecting the ball to touch down for a try of his own to a 14-0 lead.
The Force, who were round one winners over Melbourne, hit back when winger Zach Kibirige got on the outside of his opposite Suliasi Vunivalu.
While they got on the board again through ex-Brumbies hooker Folau Fainga'a, the Reds pushed the scoreline out to 29-13 by halftime and looked in full control.
With Wallabies coach Eddie Jones watching from the stands No.8 Harry Wilson impressed while Test playmaker James O'Connor looked sharp in his first run of the season.
The second half was one to forget for new Force coach Cron with the Reds piling on the misery, the men from Perth not helped by losing flanker Ollie Callan to a red card for a high tackle and their captain Michael Wells to a HIA.
Among the tryscorers Vunivalu, who made a name for himself on the same ground as a Melbourne Storm NRL player, intercepted a pass and ran 80m to score.
While he managed to touch down he pulled up just before line sparking fears he had re-injured his hamstring.
But it was only a cramp with the World Cup hopeful playing on.
With the Force down to 13 men, also losing Jackson Pugh to a yellow card for the final minutes, Flook finished with two tries as did winger Felipe Daugunu.
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