The mandatory requirement for masks at indoor workplaces and workplaces will be officially scrapped from 6pm Friday.
Masks will still be mandatory in healthcare settings, residential aged care, disability accommodation, prisons, public transport, airports, and planes.
However, masks will still be essential if people cannot socially distance.
Premier Annastacia Palaszczuk urged people to decide for themselves if they needed to wear a mask.
"Some good news, the masks can come off, but please remember, if you're in crowded situations, please think about whether or not you use it," the premier said.
"It's totally up to yourselves.
"But our numbers continue to track downwards with COVID, which is again excellent news."
Two hundred eighty-four patients remain in hospital, with 25 in intensive care with 30,377 active cases across the state.
The latest figures show 92.9 per cent of eligible Queenslanders have received one dose of a vaccine, while 90.97 per cent have had two.
Density limits will be scrapped for private homes, weddings and funerals, and there will be no restrictions in food courts, hairdressers, gyms, private venues and universities.
Deputy Chief Health Officer Peter Aitken said lifting the mandate would be a welcome relief - but said people sweating through the flood clean-up did not need to wait.
"That's a really important thing that people can get out and about and start to do more," Dr Aitken told the ABC.
"But if you're outdoors, you don't need to wear a mask.
"Don't feel that if you're outdoors, suffering, and the cleaning up in the mud, some people have got some horrible conditions to contend with. If they're outdoors doing that they don't need to wait till six o'clock tonight to take that mask off."
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