In a match played in a swirling breeze, Adelaide led by just four points midway through the second quarter before piling on 10 of the next 12 goals to set up the 19.14 (128) to 8.14 (62) win.
Josh Rachele cashed in with five goals, while Jordan Dawson tallied 27 disposals, eight clearances, two goals and 602m gained in a best-afield display on Sunday.
Tempers boiled over in the dying minutes when Eagles recruit Liam Baker pushed his forearm into the back of James Peatling's neck while the Crow was face-down on the ground.
The incident sparked a major melee that is sure to attract plenty of fines.
The percentage-boosting result ensured Adelaide (7-4) will finish the round in the top four, while West Coast (1-10) couldn't reproduce the heroics from last week's breakthrough win over St Kilda.
Adding to West Coast's woes was a serious injury to Waterman, whose right shoulder popped out when he was sandwiched in a final-quarter marking contest.
Waterman had been a rare shining light for West Coast with three goals, but his season could be over if he requires surgery.
The 27-year-old was immediately in pain and had to go to the bench to have his shoulder put back in place. He was seen with his arm in a sling after the match, and was taken to hospital for scans.
"He won't fly home tonight," West Coast coach Andrew McQualter said.
"He's clearly in a fair bit of pain. It (the shoulder) did come out, and there was some trouble getting it back in, or it might have popped out again.
"He's gone to hospital now to get some scans and we'll find out the full extent of that later on.
"Jake's one of our leaders, one of our best players. You never want to lose your leaders."
The Crows were error-riddled early against the Eagles, but once they hit their straps they were simply unstoppable.
Reilly O'Brien (45 hit-outs) was the dominant figure in the ruck, while Izak Rankine (23 disposals, six clearances, one goal) was a creative spark.
Rachele hadn't kicked five goals since his debut in 2022, and he was lapping up his efforts on Sunday.
"It's been a while - 64 games later. It's good to get another bag," Rachele told Fox Sports.
West Coast were breathing a huge sigh of relief when veteran Adelaide spearhead Taylor Walker was ruled out an hour before the first bounce.
Walker kicked bags of 10 and nine goals against West Coast in 2023, but the Crows decided it was time to rest the 35-year-old.
West Coast won the territory battle in the first half, but Adelaide's efficiency was better and the Crows turned on the afterburners in the second half to secure the easy win.
"I think maybe just a little bit of our focus had gone away from what makes us a good side," Adelaide coach Matthew Nicks said of his side's lacklustre first half.
"So to be able to fix that in the game is a great result.
"In previous years it might be one where you see four quarters of the same and we come out maybe with a small win or we lose the game."
14°C