The Microsoft-owned career network is cutting about 668 roles across its engineering, product, talent and finance teams.
"Talent changes are a difficult but necessary and regular part of managing our business," the company said in a statement.
The job cuts follow another more than 700 lay-offs LinkedIn announced in May, as well as thousands more this year from parent company Microsoft, which has owned the professional-networking service since buying it for $US26 billion ($A41 billion) in 2016.
LinkedIn keeps growing and said its annual revenue surpassed $US15 billion for the first time in the fiscal year that ended in June.
The US-based service makes money from advertisements on the platform as well as from users who pay to subscribe for premium features.
LinkedIn reports having about 19,500 employees.
Microsoft as of July had a global workforce of 221,000 full-time employees, with more than half of those in the United States.
It is adding thousands more as part of its $US69 billion acquisition of California video game-maker Activision Blizzard, which closed on Friday.
As of late last year, Activision Blizzard reported having 13,000 employees.
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