The Tigers, on the hunt for a three-peat, were emphatic against the Wanderers in the second semi-final, running out 17.12 (114) to 6.3 (39) victors.
Coached by Picola product Chris Baksh, the Tigers got off to a flying start in the contest at TIO Stadium.
Tongala product Cam Ilett and ex-Shepparton United footballers Brodie Filo and Daniel Bowles starred for the Tigers.
Shepparton and former Nathalia and Picola junior Tom Boyd was important in defence.
On the Wanderers’ team sheet, Numurkah product Tom Motlop battled hard in the loss.
Nightcliff will enjoy a week off as its opponents front up against St Mary's in the preliminary final.
St Mary's booked a spot in the preliminary final after its 14.9 (93) to 10.7 (67) win over Waratah.
Tatura's Brandyn Grenfell provided support in the win and chipped in with a goal.
In women's premier action, Pint suffered its first loss of the season in the second semi-final against Darwin.
Nathalia products Reni Hicks and Gemma Cusack tried their hardest to get Pint over the line, but it was not to be, as the Queenants went down by eight points.
Pint will get another crack at making the grand final when it comes up against Nightcliff this weekend.
In men's division one, a string of district products guided Banks to a 12.8 (80) to 6.7 (43) win over Waratah.
The first semi-final success was orchestrated by classy efforts from Moama's Jye Warren, Rumbalara's Kyal Atkinson, Shepparton's Tyler Bell, Berrigan's Will Robinson and Kyabram's Jack Castles.
The result brings an end to Benalla's Jamie Smith's season.
In the second semi-final match, Pint earned a grand final berth after overcoming Nightcliff by eight points.
Tatura products Matt Ryan (three goals), Andrew Ciavarella and Brad Ryan were the standouts for Pint.
Nathalia's Clancy Congues worked tirelessly for Nightcliff in the 7.6 (48) to 6.4 (40) loss.
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