The Dockers (6-1) have won six games in a row to put themselves firmly in the hunt for the minor premiership and will start as hot favourites against an injury-hit Bulldogs outfit on a three-match losing slide.
A big part of Fremantle's success this season has been the hot form of ruckman Luke Jackson, who has been labelled a unicorn for his ability to wreak havoc in the air and at ground level.
Jackson is averaging career highs this season in disposals (19.3), clearances (5.3), hitouts (26.7) and hitouts to advantage (9.1), as well as kicking six goals.
Although ruckman Tim English has been given the green light to return from a knee injury, the Bulldogs (4-3) face a major challenge in halting Jackson's influence.
"When he's playing like that and enforcing himself and imposing himself on the contest, it's unreal for us," Dockers forward Michael Frederick said of Jackson.
"We get a big energy boost from that. He's quick, he's skilful. As people like to say, he's a unicorn.Â
"And I think it's pretty special that we got someone like that that can roll in the ruck, roll forward as well as playing as a midfielder."
With Sean Darcy set to miss another three to five weeks with a calf injury, Fremantle will stick with their Jackson-Mason Cox ruck combination for the foreseeable future.
Pat Voss returns after missing last week through illness, but defender Judd McVee (illness) was ruled out.
The Bulldogs named Aaron Naughton (neck) after he recovered well from his scary fall last week, but there were a whopping six changes all up to the side that lost to Sydney by 66 points.
Ryan Gardner, Lachie Jaques, Lachlan Smith, Oskar Baker and Cooper Hynes were all dropped, while Adam Treloar is being managed.
English, Nick Coffield, Harvey Gallagher, Arthur Jones, Laitham Vandermeer and Lachie McNeil all come into the side.
In previous seasons, Fremantle have been vocal in their flag ambitions and wanting to secure a top-four berth.
This season they've taken a different approach, merely saying they are now "1-0" after every win they post.
"I think when you look too far ahead, sometimes it can distract you a little bit from what you need to do now," Frederick said.
"For us to sort of have that 1-0 mantra each week after a win has been good to re-set us."
Frederick kicked two goals in last week's 14-point win over Carlton.
It was just his second match of the season after suffering an unlucky ankle injury on the eve of round one, when Shai Bolton tackled him at training.
Bolton made up for it by setting up Frederick's two goals against Carlton.
"The ankle twisted the wrong way and I heard a pop kind of thing," Frederick said.
"I knew I wasn't too good. Bolton was the first one to check in on me. I was lucky I had a good pre-season before that.
"And before the game (against Carlton) he told me he would look after me."
