Vic opposition leader in COVID isolation

"My wife, my other two sons and I have returned a negative rapid test," he said in a statement on Tuesday.

He hopes to return to work for parliament sitting week next Tuesday. Deputy leader David Southwick will act as party leader in his absence.

Mr Andrews is also spending a week in isolation after he tested positive for COVID-19 in a rapid antigen test on Monday. He said his symptoms were mild.

Deputy Premier James Merlino will be acting premier until April 4.