Anthony Albanese will use his annual closing the gap speech on Thursday to announce a $144 million boost to Indigenous health to upgrade more than 100 services in cities and regional areas.
The prime minister will argue addressing heath outcomes is critical in improving multiple closing the gap outcomes.
"Many of these clinics had not seen a dollar of new investment for decades," he will say.
"All levels of government will work together to see this funding deliver a change in outcomes."
Mr Albanese will also announce plans to reduce prices on essential items at all remote grocery stores in Indigenous communities, following a successful trial.
Prices on 30 items like flour, cereal and toothpaste would be in line with those in the city across 225 remote stores
"We all know what it means to be able to put healthy food on the table.The difference it makes for mums expecting a baby, for a child's health and growth, even for their ability to concentrate at school," the PM will say.
Mr Albanese's address will reveal four of the closing the gap outcomes are on track to be met, with a further six targets being improved upon.
"Based on progress to date, later this year we expect confirmation that the target of 95 per cent of Aboriginal and Torres Strait Islander children enrolled in preschool has been achieved," he will say.
"There are four areas where progress is stalled, or going backwards.The most urgent is suicide. Suicide shatters families, it tears apart communities."
The prime minister will also use the speech to warn against any pre-emptive declaration of failure in closing the gap in outcomes.
"Talk of failure dismisses the aspirations and achievements of Indigenous Australians. It ignores the leaders and communities who are changing lives," he says.
"Failure is a word for those who have stopped trying - or given up listening.
"The challenges facing us are significant, complex and connected, with causes that reach back generations. But that does not render us powerless - it makes each act of change powerful."
The closing the gap speech comes after the government announced the roll out of a 10-year plan on Tuesday to address domestic and family violence against Indigenous women and children.
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