The Harvest Moon musician has hit out at Amazon founder Jeff Bezos and his company in a candid statement posted on his Neil Young Archives blog.
Young condemned Bezos' support of the Donald Trump administration and urged fans to "buy local", "support your community" and "do the right thing".
"Forget Amazon and Whole Foods (supermarket chain owned by Amazon). Forget Facebook. Buy local. Buy direct. Bezos supports this government. It does not support you or me," the rock legend wrote.
"The time is here. Forget Amazon. Soon my music will not be there. It is easy to buy local. Support your community. Go to the local store.
"Don't go back to the big corporations who have sold out America. We all have to give up something to save America from the Corporate Control Age it is entering.
"They need you to buy from them. Don't. They shut down our government. Your income. Your safety. Your family's health security. Take America Back.
"Together, stop buying from the big corporations, support local business. Do the right thing. Show who you are."
Young - who recently removed himself from Instagram and Facebook - did not confirm whether he's just pulling his music from Amazon's streaming service or also removing physical copies from sale via the retail giant.
The move comes three years after the rocker removed his music from fellow streamer Spotify to protest the platform's distribution of The Joe Rogan Experience podcast amid concerns it was spreading misinformation about vaccines.
However, Young later returned his music to the platform in 2024 admitting other streamers were also hosting similar podcasts and he could not remove all his work from the online world.
In a statement at the time, Young explained: "My decision comes as music services Apple and Amazon have started serving the same disinformation podcast features I had opposed at Spotify.
"I cannot just leave Apple and Amazon, like I did Spotify, because my music would have very little streaming outlet to music lovers at all, so I have returned to Spotify, in sincere hopes that Spotify sound quality will improve and people will be able to hear and feel all the music as we made it.
"Qobuz and Tidal, where my music is presented, are all high-res as well."
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