The Saints could only manage two goals for the contest themselves, with the Bulldogs running out 25-point victors.
Toogood added seven disposals, two marks and a tackle to her pair of goals in the Sunday clash.
Across the other side of the country a strong contingent of Goulburn Valley exports took to the field for Geelong in its fixture against Fremantle.
Mooroopna's Millie Brown made her debut alongside Benalla's Becky Webster and Kyabram product Julia Crockett-Grills, collecting eight possessions along the way.
Crocket-Grills snared 22 disposals and five marks to put in a stellar performance, while Webster racked up 21 and seven — along with two tackles — in the season-opener.
The Cats stayed with the Dockers for the majority of the match before the home side drew away late in a 16-point triumph.
Friday night's 48-14 win for Carlton also had another familiar face debut, with Shepparton's Grace Egan tasting action on the big stage for the first time.
The midfielder had 11 touches and six tackles in the win for the Blues and was ferocious at the contest, standing up to some attempted rough-and-tumble tactics from the Tigers on a number of occasions.
Fellow Shepparton product Angela Foley booted a goal and had 11 disposals for Adelaide on Saturday night, but could not help her Crows over the line in a 13-point loss to Brisbane.