At least three people were in a critical condition and six others were seriously injured in the incident in the early hours of Saturday morning, the city's fire department said.
Los Angeles City Fire Department public information officer Captain Adam Van Gerpen said at least three of the injured were in critical condition.
Van Gerpen said a line of people - most of them female - were waiting to enter a nightclub when they were struck by a Nissan Versa that also hit a taco truck and valet stand.
Paramedics discovered one of the patients had a gunshot wound, Van Gerpen said.
"This is under police investigation," he said.
"This will be a large investigation with the LAPD."
Videos posted on X showed roads being sealed off and patients being taken away in ambulances.
People inside the club came out to help the victims in the minutes before emergency crews arrived, he said.
"They were all standing in line going into a nightclub. There was a taco cart out there, so they were ... getting some food, waiting to go in. And there's also a valet line there," he said.
"The valet podium was taken out, the taco truck was taken out, and then a large number of people were impacted by the vehicle."
Authorities gave no immediate details on the cause of the incident or the identity of the driver.
The location was near a music venue, CNN reported.
The incident happened just before 2am local time (0900 GMT), the fire department said.
with AP
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