Currently sitting atop the Goulburn Valley League ladder, United was far too strong for the Tigers at Moon Oval.
The Demons held a slight four-goal lead at three-quarter time, however, powered past the home side with a 17-8 final term to clinch a 56-43 win.
Meanwhile, a superb opening quarter from Seymour helped secure a 45-34 win against competition dark horse Mooroopna.
The Lions rocketed out of the gates with a stunning 15-5 first term, with their slick ball-use into the attacking end on show.
But it was their defensive pressure through the midcourt and defence that was delighting home fans.
Sarah Szczykulski and Meg Grbac led the way for Seymour in defence, while coach Elle McDonald starred with her talents through the midcourt.
Mooroopna's Paigan Impey battled hard in the midcourt, often duelling against McDonald for the hard ball.
Ella Ogier and Shelby Britten battled hard for the Cats and were the other standout performers in the loss.
Seymour clings onto second spot — by percentage ahead of Echuca — as the Cats drop back to sixth after Shepparton held on to defeat Benalla.
The Bears looked set to cruise through for an easy win at three-quarter time, until the Saints fought back in the last.
Trailing by nine goals at the final break, Benalla scored 11-5 to fall three goals short of a miracle win.
Shepparton's Ash Cann and Laura Scott performed brilliantly, while Grace Amarant, Kylie Doff and Chloe Hill were Benalla's standouts.
Kyabram's classy third term helped secure an impressive nine-goal win on the road against Mansfield.
With scores even at half-time, the Bombers went on to sink 13-6 in the third term, before holding on to claim a 39-30 win.
Tatura clinched its second win of the season with a thumping 65-37 win against Euroa.
Alex Bertram and Steph Hicks gave the Bulldogs the upper hand, while Jacquie James continued her sublime season with another strong outing.
Eliza Hoare fought bravely for Euroa alongside teammates Kelsey Moylan and Jenna Richardson.
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