Police executed a warrant at a house in Kialla this morning where a commercial quantity of cannabis was located along with a sophisticated hydroponic set up.
Two men from Melbourne were arrested as part of the investigation and will attend the Shepparton County Court today.
The arrest comes after investigators from the Shepparton Divisional Tasking Unit conducted an operation into a series of cannabis crop houses across Victoria.
Police executed warrants at two other addresses in Mooroopna and Moe as part of the investigation.
Police said the cannabis seized was a commercial quantity of a high dollar figure.